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4.8

Rated 4.8 out of 5 stars

4.8 Stars (1,540 Reviews)

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1st Trimester Brain Boost Duo*

Extra support for baby's brain development*

Doctor–approved to safely take together

Prenatal

Anti-Nausea

Brain Health

1st Trimester Prenatal Pack

• Foundational 1st trimester prenatal routine

• Helps ease nausea in the first trimester*

Choline Boost

• Helps build baby's brain and spine*

• Extra choline for what pregnancy demands*

• RECOMMENDED

Subscribe & Save 15%

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Delivery every 30 days

$74.90

/ Month$88.12

• One time purchase

$88.12

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Delivery every 60 days

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$74.90

$88.12

View Supplemental Facts

1st Trimester Brain Boost Duo*

Doctor-backed regimen

Add to Cart

$74.90

/ Month$88.12

• 3rd party tested

• Doctor Formulated

• Complimentary Shipping

Description

The 1st trimester is when your baby's brain and spine are actively building. Choline is one of the most important nutrients during early pregnancy for the role it plays in baby’s brain development, yet 95% of pregnant women don’t meet their daily choline needs.

That’s why we paired our two best selling products together to support your baby during the first trimester with a doctor-approved prenatal routine that covers your nutritional foundation. Pairing our 1st Trimester Prenatal Pack with 120mg of choline with our Choline Boost adds 550mg to get you to the 930mg that research suggests to support your baby's brain development and your own brain health during pregnancy .*

This duo includes:

• 1st Trimester Prenatal Pack

• Choline Boost

How This Duo Works Together

Your 1st Trimester Prenatal Pack is a comprehensive prenatal vitamin routine with targeted nutrition for weeks 0-13 of pregnancy, including methylfolate, iodine, DHA, and B6 with ginger to help ease nausea.* Choline Boost adds 550mg of bioavailable, clinically-studied choline on top of your prenatal foundation.

Directions

1st Trimester Prenatal Pack: Take one pack daily with food and a full glass of water.

Choline Boost: Take 1-2 capsules daily with food and water depending on your daily diet.

As with any supplement, consult your doctor before use if you are pregnant, nursing, have a medical condition or are taking any medications.

Inside 1st Trimester Prenatal Pack

Core Prenatal

Supplemental Facts - Supplement Facts

Omega DHA + EPA

Supplemental Facts - Supplement Facts

Folate + Anti-Nausea Blend

Supplemental Facts - Supplement Facts

Inside Choline Boost

Choline Supplement

Supplemental Facts - Supplement Facts

This offer expires on Tuesday, May 26, 2025 at 11:59pm PT. Save 20% for your first month. Cannot be combined with other offers, discounts or applied to prior purchases. Limited to one use per customer and new customers only. Offer excludes gift cards, apparel and accessories. Please note that we limit subscriptions to one unit per customer for any specific product. (That said, feel free to subscribe to multiple products!)

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Your Doctor-Backed, Stage-Specific Regimen

Dr. Banafsheh Bayati

Board-Certified OB/GYN | Medical Co-Founder, Perelel

"Our 1st Trimester Prenatal Pack with Choline Boost Duo has you covered for the dietary challenges presented during this critical time in early pregnancy. During fetal and placental development, nutritional support is key and optimizing through diet and supplementation should be targeted. The fatigue and dietary intolerance during this time can present a challenge. Maximizing support through supplements that enhance the needs of this vital stage is our goal at Perelel."

1st Trimester Prenatal Pack

• Complete prenatal vitamin routine
• Helps ease nausea with B6 and ginger*
• Supports baby's early development*

Quick view +

Choline Boost

• Supports baby's brain and spine development*
• Clinically studied for optimal absorption
• Supports mom’s memory and brain*

Quick view +

• 1st Trimester Prenatal Pack

• Choline Boost

Core Prenatal Vitamin

2 Capsules Per Pack

Foundational Prenatal Nutrition

A blend of clinically-dosed vitamins and minerals so your baseline nutrition is always covered, and trimester-specific nutrients can be layered in exactly when you need them.

Supports Healthy Iron Levels

Iron deficiency affects more than 50% of pregnant women. This pack includes Ferrochel® iron, clinically studied for better absorption and gentler digestion than standard iron forms.*

Supports Baby’s Thyroid Development

Iodine requirements increase more than 50% during pregnancy, yet 23% of pregnant women fall short daily. We include 150mcg iodine at the dose recommended by the American Thyroid Association and Endocrine Society.

Omega DHA + EPA

1 Softgel Per Pack

Supports Baby’s Brain and Eye Development*

Omega DHA and EPA support baby's developing brain, eyes, and nervous system.* EPA is essential for transferring DHA across the placenta, which is why we include both in every pack.*

Supports Mom’s Mood and Heart Health*

Omega-3s play a key role in supporting mood balance and cardiovascular health during pregnancy, when maternal DHA reserves are actively being shared with baby.*

Folate + Anti-Nausea Blend*

1 Capsule Per Pack

Helps Ease Morning Sickness*

This same capsule includes Vitamin B6 and ginger root to help relieve occasional nausea during early pregnancy.*

Supports Healthy Early Neural Development*

This capsule adds 825mcg DFE of methylfolate on top of what's already in your core prenatal, bringing your total to 1,525mcg DFE, when the neural tube closes and folate demand is at its highest in the first trimester.*

Choline Chloride

Supports maternal and infant brain health*

Choline is key for cognitive functions, supporting both maternal brain health and fetal brain and neural tube development*

Clinically proven bioavailable choline*

The first choline source that has been clinically proven to be bioavailable in pregnancy - to support both mom and baby*

Supports baby’s cognitive function from pregnancy into childhood*

Taking additional choline during pregnancy or breastfeeding supports infant brain health that continues well after birth–supporting a young child's attention and cognition*

Doctor-Backed, 3rd Party Tested

We hold our products— and your health—to the highest standards. Here's what you can expect for every Perelel Product:

• Rigorous vetting & testing at every stage of manufacturing
• Meticulous formulation in partnership with our Perelel Panel
• Doctor-recommended doses to ensure nutrients make an impact
• Every ingredient is backed by research
• Micro, heavy metal and purity testing of every batch
• Made in the USA in FDA Registered and Inspected Facilities
that are cGMP certified

Learn More

Frequently Asked Questions

• General

Questions

• 1st Trimester Prenatal Pack
• Choline Boost

What is the benefit of a duo?Chevron icon

The benefit is to have a doctor-approved duo tailored to your specific wellness needs. While addressing your goals, our duo simplifies your wellbeing routine, eliminating guesswork about which supplements to take when and which supplements are safe to take together.

How are the products in the duo selected?Chevron icon

Each product in our doctor-approved duo is carefully chosen by our expert team of board-certified doctors. They review scientific research and clinical data, combined with practical insights from real patient experiences, to create a comprehensive regimen that addresses the unique needs and symptoms of each stage and safely pairs supplements together.

Why are the First Trimester Prenatal Pack and Choline Boost paired together?Chevron icon

Your prenatal pack provides 120mg of choline, a solid foundation, but short of the 930mg research supports for optimal fetal brain development. Choline Boost adds 550mg to bridge that gap, bringing your combined supplement intake to 670mg and meaningfully closer to what the research actually supports.* The first trimester, especially the first 6 weeks, is when choline matters most. Your baby's brain and spine are actively forming, making this the most critical window to optimize your levels.*

Who is this duo best for?Chevron icon

Any woman in her first trimester. The 1st Trimester Prenatal Pack covers your nutritional foundation, and Choline Boost adds the dedicated choline support your baby's developing brain and spine need throughout the first trimester.*

What if I only need one product in the duo?Chevron icon

While our duos offer a convenient routine for your specific wellness goals, each supplement is also available for individual purchase. Simply select the specific product you need from our catalog—no duo required. Shop all vitamins and supplements here.

How do I make product swaps when I move into a different stage?Chevron icon

We understand that your needs evolve over time. To update your products as you move into a new stage, simply visit your Subscriber Portal and select the “Manage Your Subscriptions” option. From there, you can swap products to better match your stage-specific needs.

Need guidance? Our customer support team is always happy to help you choose the right supplements for where you are. You can contact us at any time.

Can I customize or swap items in the duo?Chevron icon

Yes, you can! We offer the flexibility to customize your duo so it fits your unique needs. You can easily swap products, add new ones, or remove items through your Subscriber Portal. Whether your goals change or need something new, your duo can evolve with you.

If you need help choosing the right combination, our team is here to support you. You can contact us at any time.

Can I add one-time products to my duo order?Chevron icon

Yes, during checkout or through your Subscriber Portal you have the option to add one-time products to your duo order. It’s a great way to try something new without changing your regular subscription. These items will ship with your next bundle but won't be included in future orders unless you add them again.

Will items in the duo ship together or separately?Chevron icon

All items in your duo will always ship together in a single package. This ensures you receive your full order at the same time, making it easier to maintain your routine without any interruptions.

How does the subscription work? Will I need to do anything on my end to move on to the next trimester pack?Chevron icon

Once we collect your due date, your subscription will automatically update alongside your pregnancy and through postpartum with no extra work needed on your end!

Do these prenatal vitamins contain folic acid?Chevron icon

We use Methylfolate, the active form of folic acid, which is clinically proven to increase serum folate levels.

Since folate is crucial for early pregnancy, it was important to our medical panel to include the most bioavailable form of folate possible—in the form of Methylfolate in our prenatal vitamin formulas. "Folic acid is less expensive, [which] leads to the terms folate and folic acid being interchangeable," says Dr. Amber Samuel, a maternal-fetal medicine doctor and Perelel Panel member. "We know that while everyone has to convert folic acid for it to be useful, [it's] an added step, decreasing bioavailability. And some women cannot due to MTHFR mutations."

To learn more about the difference between Folate and Folic Acid, you can read our blog post here.

Are Perelel products third-party tested?Chevron icon

Yes, we complete third-party testing on all of our products to confirm purity and potency. All of our vitamins are made in FDA Registered and Inspected Facilities, which meet FDA 21 CFR 111 guidelines and are also cGMP Certified. All raw materials for our vitamins are tested directly prior to production to ensure their purity and quality. COAs are performed on every batch of manufactured vitamins to ensure final product integrity and quality, which includes testing for heavy metals, microbes, allergens and contaminates. We then complete third-party testing for heavy metals, microbes and potency to confirm our products are safe under USP standards.  In addition, our pre and postnatal formulas have earned us certification from the Clean Label Project, a leading nonprofit that sets one of the industry's highest standards for consumer transparency. We’re proud to have earned Clean Label Project’s highest honor, the Purity Award!

If you're interested in learning more, check out our blog post here on heavy metals.

I'm TTC. How early should I start taking prenatal vitamins?Chevron icon

We recommend starting with our [Conception Prenatal Support Pack](/content/products/conception-support-pack "Conception Support Pack*"/index.html)*, which was specifically formulated by fertility doctors and OB/GYNs to prepare your body for pregnancy. It contains our Core Prenatal, so that your baseline nutritional needs are covered when you get pregnant—before you even know it! Once you have a positive pregnancy test, you can reach out to us or update your subscription directly in your account portal to the 1st Trimester Prenatal Pack!

How many pill packages come in one order?Chevron icon

Each monthly Pack contains 30 daily sachets (with 4 pills each) to cover all your needs during the 1st trimester.

I just ordered my 1st Trimester Pack but I have some of my Conception Prenatal Support Pack left. Will the Conception Prenatal Support Pack support my needs while I wait for my Trimester Pack to arrive?Chevron icon

Our doctors formulated our Conception Prenatal Support Pack* to support your needs for early pregnancy, including a Core Prenatal and additional folate, so you're good to continue taking your Conception Prenatal Support until your 1st Trimester Prenatal Pack arrives!

I technically just moved into my second trimester but I'm still finishing up my 1st Trimester Pack. Should I finish my 1st Trimester Pack or wait for my 2nd Trimester Pack to arrive?Chevron icon

While the timing of when you start your vitamins with us doesn't always exactly align with your trimester, rest assured all of our packs will keep your needs covered during any overlap weeks! Feel free to finish out your current pack before switching to your new one.

What makes Perelel's Prenatal Pack different than other prenatals?Chevron icon

Perelel is the first and only prenatal vitamin brand co-founded by an OB/GYN. For each of our formulations, our medical co-Founder, Dr. Bayati, partners with a panel of leading doctors and women's health experts—drawing on both the latest scientific research and their own clinical insights to help select high-quality ingredients in their most bioavailable forms, in clinically-tested doses.

Our bodies and baby's needs change so much during pregnancy. Unlike most one-size-fits-all prenatal vitamins, our Trimester Packs were specifically designed to change with you—delivering targeted nutrition and symptoms relief when you need it most.

How does my subscription work?Chevron icon

Our products run on a monthly subscription to make sure you never run out of your vitamins. Your subscription will automatically update alongside your due date so you receive the right pack for your trimester and into postpartum.

We account for shipping time and will automatically move you into the next trimester pack as you start to approach it. You will receive an email 5 days prior to any shipment just in case you need to make any adjustments (such as changing packs or moving back a shipment).

We follow the American College of Obstetricians and Gynecologists™ (ACOG) defined trimesters:

• 1st Trimester: Week 0 through Week 13
• 2nd Trimester: Week 14 through Week 27
• 3rd Trimester: Week 28 through Week 40+

Always feel free to contact us at hi@perelelhealth.com if you have any specific questions or want to make any changes.

Are these vitamins covered by FSA or HSA?Chevron icon

This product is FSA/HSA eligible. Learn more here.

What other products are pregnancy safe that I can take with this?Chevron icon

Synbiotic Greens Powder, Cellular Hydration Powder, Triple-Support Protein, Sleep Support, Daily Probiotic and Daily Iron Ease are all safe for pregnancy and can be safely paired with your Prenatal Multivitamin Pack.

How big are the pills? Chevron icon

Our supplements are designed to be easy to swallow. Here's a visual size comparison with a penny to help you see the actual size of each product.

How do I know if I need Choline Boost?Chevron icon

Most women don’t get enough choline from diet alone and it is essential for brain, liver, and cellular function and health. The recommended amount of choline for pregnant women is 450 mg and breastfeeding is 550 mg per day. Our daily packs provide enough choline to meet that requirement alongside a healthy diet, but some women may need or want an additional boost or to help close the gap. All women can benefit from meeting the daily recommended intake of choline to support cognition and cellular health at every stage of life (especially perimenopause and beyond when decreased estrogen levels mean that the body is less efficient at naturally producing acetylcholine, which choline is needed for and can contribute to brain fog).

Can I take Choline Boost on its own?Chevron icon

Yes! Choline is an essential nutrient that is required for neurotransmitter synthesis, contributes to cell membrane structure, is involved in methylation functions, and supportive of liver health. It is beneficial to all women, especially as most don’t get enough choline from their diet.

Are Perelel products third-party tested?Chevron icon

If you're interested in learning more, check out our blog post here on heavy metals.

Got more questions?

See our full FAQ or chat with our team

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

4.8

Rated 4.8 out of 5 stars

Based on 1,540 reviews

5 Rated out of 5 stars

1.3k

Total 5 star reviews: 1.3k

4 Rated out of 5 stars

159

Total 4 star reviews: 159

3 Rated out of 5 stars

34

Total 3 star reviews: 34

2 Rated out of 5 stars

9

Total 2 star reviews: 9

1 Rated out of 5 stars

10

Total 1 star reviews: 10

97% would recommend these products

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1,540 reviews

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• MG

Mikaela G.

Verified Buyer

Reviewing

1st Trimester Prenatal Pack

I recommend this product

Rated 5 out of 5 stars

3 days ago

Easiest Decision

These packs are the best decision I made for my pregnancy. The range of things these packs have keep my mind at ease while going through my first pregnancy. They make prenatal care so easy and has helped with some of the 1st Trimester symptoms better.

Read MoreRead more about this review

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Yes, this review from Mikaela G. was helpful. 0 people voted yesNo, this review from Mikaela G. was not helpful. 0 people voted no

• S

Stephanie

Verified Buyer

Reviewing

1st Trimester Prenatal Pack

I recommend this product

Rated 5 out of 5 stars

4 days ago

10/10 recommend

I have been loving this product. I’ve had very little nausea my first trimester. I think it’s because it’s so easy to remember to bring a pack with me and take them on the go. They definitely have an after taste, but most vitamins do. I’m confident that I’m getting the nutrients I need for me and my baby.

Read MoreRead more about this review

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• BH

Bessy H.

Verified Buyer

Reviewing

1st Trimester Prenatal Pack

I recommend this product

Rated 5 out of 5 stars

4 days ago

No Vomiting Only Mild Nausea

I was taking the Nature prenatals but I felt like I wasn’t giving my baby the best of what I can give so I did a little research and perelel really caught my attention especially because each trimester you take what your baby and yourself needs. I was so afraid of morning sickness and thanks to the prenatal having ginger I only had mild nausea! I’m so excited to try the second and third trimester packs don’t think twice about buying these prenatals they are so worth it.

Read MoreRead more about this review

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Yes, this review from Bessy H. was helpful. 0 people voted yesNo, this review from Bessy H. was not helpful. 0 people voted no

• GF

Grace F.

Verified Buyer

Reviewing

1st Trimester Prenatal Pack

I recommend this product

Rated 5 out of 5 stars

1 week ago

the best & easiest vitamins

i love how easy these are to take daily & travel with so you’re always consistent. i’ve struggled with bad morning sickness but take these at night & they go down so easy.

Read MoreRead more about this review

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Yes, this review from Grace F. was helpful. 0 people voted yesNo, this review from Grace F. was not helpful. 0 people voted no

• PS

Pristine S.

Verified Buyer

Reviewing

1st Trimester Prenatal Pack

I recommend this product

Rated 5 out of 5 stars

1 week ago

Solid!

I have been taking perellel and started conception pack and now that Im pregnant, I have been taking the 1st trimester prenatal pack. Its very convenient for me because almost everything I need is in the packet. And I dont have to worry about taking all the bottles with me since it comes in one packet everyday. It makes my day easier especially when Im rushing to go to work. It doesnt make me feel nauseous too which Im grateful for.

Read MoreRead more about this review

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3rd trimester Prenatal Pack

after birth

Mom multi support pack

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## Nutrition Facts

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## Inside 1st Trimester Prenatal Pack

### Core Prenatal

Supplemental Facts - Supplement Facts

### Omega DHA + EPA

Supplemental Facts - Supplement Facts

### Folate + Anti-Nausea Blend

Supplemental Facts - Supplement Facts

## Inside Choline Boost

### Choline Supplement

Supplemental Facts - Supplement Facts

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